John J V McMurray Selected Research

Endothelin Receptor Antagonists

11/2022	Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Long-Term Response to Atrasentan in Patients With Diabetic Kidney Disease.
1/2022	Increase in BNP in Response to Endothelin-Receptor Antagonist Atrasentan Is Associated With Incident Heart Failure.
11/2021	Early Response in Albuminuria and Long-Term Kidney Protection during Treatment with an Endothelin Receptor Antagonist: A Prespecified Analysis from the SONAR Trial.
1/2021	Individual Atrasentan Exposure is Associated With Long-term Kidney and Heart Failure Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease.
11/2019	Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial.
1/2017	Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials.
11/2007	Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials.

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John J V McMurray Research Topics

Disease

626	Heart Failure 05/2024 - 01/2002
122	Myocardial Infarction 05/2024 - 11/2003
100	Type 2 Diabetes Mellitus (MODY) 05/2024 - 03/2005
81	Stroke (Strokes) 04/2024 - 06/2004
76	Chronic Renal Insufficiency 03/2024 - 03/2005
65	Atrial Fibrillation 05/2024 - 03/2005
48	Left Ventricular Dysfunction 05/2024 - 11/2003
35	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 09/2004
34	Cardiomyopathies (Cardiomyopathy) 05/2024 - 08/2010
33	Systolic Heart Failure 01/2021 - 11/2007
28	Hypotension (Low Blood Pressure) 05/2024 - 09/2003
28	Anemia 02/2024 - 12/2004
27	Diabetes Mellitus 11/2023 - 09/2004
23	Chronic Kidney Failure (Chronic Renal Failure) 05/2024 - 05/2009
20	Hypertension (High Blood Pressure) 03/2024 - 06/2004
19	Renal Insufficiency (Renal Failure) 04/2024 - 12/2012
19	Sudden Death 01/2024 - 10/2004
18	Heart Diseases (Heart Disease) 05/2024 - 02/2011
17	Hyperkalemia 12/2023 - 10/2004
17	Acute Coronary Syndrome 01/2023 - 05/2008
16	Chronic Obstructive Pulmonary Disease (COPD) 03/2024 - 03/2009
15	Albuminuria 01/2023 - 07/2011
13	Dyspnea (Shortness of Breath) 01/2023 - 07/2005
12	Frailty 05/2024 - 06/2014
11	Glucose Intolerance 12/2020 - 04/2010
10	Disease Progression 11/2023 - 08/2006
10	Neoplasms (Cancer) 01/2023 - 03/2005
10	Embolism (Embolus) 02/2015 - 03/2005
10	Hemorrhage 01/2015 - 05/2008
9	Infarction (Infarctions) 01/2024 - 09/2004
9	Kidney Diseases (Kidney Disease) 12/2023 - 04/2011
9	Inflammation (Inflammations) 01/2022 - 12/2009
8	Respiratory Sounds (Crackle) 05/2024 - 05/2019
8	Coronary Disease (Coronary Heart Disease) 01/2024 - 06/2004
8	Edema (Dropsy) 01/2023 - 11/2007
7	Coronary Artery Disease (Coronary Atherosclerosis) 12/2023 - 04/2007
7	Heart Arrest (Cardiac Arrest) 01/2022 - 09/2004

Drug/Important Bio-Agent (IBA)

130	dapagliflozinIBA 05/2024 - 01/2019
113	sacubitril and valsartan sodium hydrate drug combinationIBA 05/2024 - 10/2012
88	Brain Natriuretic Peptide (Natrecor)FDA Link 05/2024 - 04/2007
71	Valsartan (Vals)FDA Link 05/2024 - 11/2003
69	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 05/2024 - 01/2002
69	Neprilysin (Neutral Endopeptidase)IBA 03/2024 - 10/2012
58	candesartanIBA 04/2024 - 09/2003
53	Angiotensin Receptors (Angiotensin II Receptor)IBA 03/2024 - 07/2010
52	pro-brain natriuretic peptide (1-76)IBA 05/2024 - 03/2009
49	CreatinineIBA 04/2024 - 09/2004
42	Mineralocorticoid Receptor AntagonistsIBA 05/2024 - 10/2004
42	Angiotensin Receptor AntagonistsIBA 05/2024 - 09/2003
42	Enalapril FDA LinkGeneric 01/2023 - 01/2011
40	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 06/2009
37	paragonIBA 05/2024 - 01/2017
37	Biomarkers (Surrogate Marker)IBA 12/2023 - 07/2007
36	Natriuretic PeptidesIBA 05/2024 - 03/2009
33	Eplerenone (Inspra)FDA LinkGeneric 05/2024 - 06/2009
32	SodiumIBA 04/2024 - 08/2015
29	Sodium-Glucose Transporter 2 InhibitorsIBA 05/2024 - 01/2018
29	Darbepoetin alfa (Aranesp)FDA Link 01/2022 - 03/2005
28	Sodium-Glucose Transport ProteinsIBA 05/2024 - 01/2018
25	Rosuvastatin Calcium (Crestor)FDA Link 01/2017 - 11/2007
24	DiureticsIBA 05/2024 - 07/2010
24	aliskiren FDA Link 01/2023 - 05/2008
21	Irbesartan FDA LinkGeneric 03/2024 - 02/2008
21	Hemoglobins (Hemoglobin)IBA 01/2023 - 02/2006
20	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2024 - 09/2003
20	AlbuminsIBA 01/2024 - 02/2009
18	Insulin (Novolin)FDA Link 12/2023 - 09/2004
16	omecamtiv mecarbilIBA 01/2024 - 03/2016
15	apixabanIBA 01/2022 - 03/2010
14	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2023 - 09/2004
14	Warfarin (Coumadin)FDA LinkGeneric 01/2022 - 03/2005
13	C-Reactive ProteinIBA 11/2021 - 03/2009
12	Troponin T (Troponin T1)IBA 10/2022 - 10/2011
12	AngiotensinsIBA 09/2022 - 09/2004
11	Spironolactone (Aldactone)FDA LinkGeneric 05/2024 - 08/2004
11	HematinicsIBA 01/2023 - 07/2009
10	SymportersIBA 04/2024 - 01/2019
10	IronIBA 03/2024 - 08/2010
10	TroponinIBA 01/2024 - 01/2011
10	PotassiumIBA 01/2023 - 11/2007
10	AldosteroneIBA 06/2022 - 06/2009
9	Glucagon-Like Peptide-1 Receptor AgonistsIBA 02/2024 - 10/2018
9	Nateglinide (Starlix)FDA LinkGeneric 01/2018 - 04/2010
9	Captopril (Capoten)FDA LinkGeneric 07/2009 - 11/2003
8	Ramipril (Altace)FDA LinkGeneric 03/2024 - 01/2021
8	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2023 - 01/2014
8	Peptides (Polypeptides)IBA 01/2023 - 11/2007
8	Cardiac MyosinsIBA 01/2023 - 03/2016
8	AtrasentanIBA 11/2022 - 11/2019
8	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 06/2017 - 01/2002
7	Erythropoietin FDA Link 02/2024 - 02/2007
7	GSK1278863IBA 02/2024 - 12/2021
7	Glucagon-Like Peptide-1 ReceptorIBA 02/2024 - 09/2015
7	AnticoagulantsIBA 11/2022 - 09/2009
7	Endothelin Receptor AntagonistsIBA 11/2022 - 11/2007
7	Renin InhibitorsIBA 04/2016 - 05/2008
6	empagliflozinIBA 05/2024 - 01/2021

Therapy/Procedure

192	Therapeutics 05/2024 - 09/2003
14	Patient Readmission 01/2023 - 05/2006
8	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2022 - 08/2010